The stimulant effects of piperazines are similar to MDMA ecstasy but dose for dose they are not as potent. Agitation, vomiting, stomach pain, fits, irregular heart rhythms, diarrhoea, allergic reactions and fever have been reported.
As stimulant drugs, piperazines are particularly risky if taken by anyone suffering from high blood pressure or a heart condition. And you may not know that you have a pre-existing heart condition.
In rare cases, users may suffer from serotonin syndrome, which can cause high blood pressure and be fatal. The chemical composition of substances sold as piperazines are changing all the time, which is why you can never be sure of what you're getting and how it could affect you.
Mixing piperazines with alcohol can be particularly dangerous - the effects of these two substances interact, and you may also be less in control, making use much riskier. Early studies suggest that you can become dependent.
It is very similar to amphetamine use, i. Supplying someone else, even your friends, can get you up to 14 years in prison, an unlimited fine or both.
Like drink-driving, driving when high is dangerous and illegal. If the police catch people supplying illegal drugs in a home, club, bar or hostel, they can potentially prosecute the landlord, club owner or any other person concerned in the management of the premises.
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects.
All rights reserved. MT , they can also act as opioids. Opioids belong to a chemically diverse group of central nervous system depressants. They bear structural features that allow binding to specific opioid receptors, resulting in morphine-like effects e. Piperazines have been found to act as stimulants as a result of dopaminergic, noradrenergic, and predominantly serotoninergic effects produced in the brain. The majority of pharmacological studies of piperazines have focused on BZP and have indicated that it produces toxic effects similar to amphetamine and other sympathomimetics.
According to animal studies, its effects are less potent than amphetamine, methamphetamine and MDMA [10]. In New Zealand, toxic seizures and respiratory acidosis after the use of BZP alone or in conjunction with other drugs were reported from three patients [13].
Another study of 61 patients reported toxic effects of BZP, with two cases presenting life-threatening toxicity [14]. Hyperthermia, rhabdomyolysis and renal failure associated with BZP ingestion have also been reported [15].
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